What is PDRN?

PDRN stands for Polydeoxyribonucleotide. It’s a naturally derived compound made from purified salmon DNA fragments—and before you say “wait, fish DNA?”, stay with us! These fragments are biocompatible, which means your body recognizes and accepts them easily.

PDRN works on a cellular level, helping to:

  • Stimulate skin regeneration

  • Repair damaged tissue

  • Boost collagen and elastin production

  • Reduce inflammation and promote healing

In simpler terms: it tells your skin to act younger, heal faster, and stay stronger.

A Little History

PDRN was first developed in the medical field, used for healing wounds, burns, and even diabetic ulcers. It was originally injected to stimulate tissue repair and regeneration. As researchers noticed the incredible effects on skin texture, tone, and elasticity, it was soon embraced by the aesthetics world—especially in South Korea, where innovation in skincare leads the way.

Today, PDRN is a staple in many Korean regenerative facial treatments, including the advanced facials we offer here at Gleam Esthetika.

Why We Love It (and You Will Too)

What makes PDRN unique is how deeply restorative it is. While many ingredients sit on the surface, PDRN works below, in the dermis, encouraging your skin to rebuild itself from the inside out.

Clients who include PDRN facials in their regular skincare routine often notice:

  • Smoother, more radiant skin

  • A visible reduction in fine lines and redness

  • Faster recovery after treatments like microneedling or extractions

  • Strengthened skin barrier over time

AO Medical Products We Use

We incorporate PDRN into our treatments through advanced Korean skincare by AO Medical, a professional brand known for its clinical results and clean formulations. These products are formulated with PDRN, growth factors, and healing botanicals—ideal for compromised, aging, or sensitized skin.

Some of our AO Medical favorites include:

  • Hevatox Recovery Ampoule – packed with PDRN and peptides to deeply repair and calm the skin

  • Hevatox Exfoliating Pads – a gentle way to renew skin texture while prepping it to absorb healing ingredients

  • Cell Active Booster – combines PDRN and skin-loving nutrients to enhance elasticity and glow

  • Caviplla O2 Serum (TOV Medical HOP+) – Infused with PLLA (Poly-L-Lactic Acid) and PDRN, this oxygenating serum firms, plumps, brightens, and boosts collagen. Its foaming action drives active ingredients deep into the skin while oxygen supports cellular regeneration.

These products are used in our signature Korean facials, which are layered with oxygen infusion, LED therapy, and lymphatic massage for a deeply restorative experience.


Beauty Starts From Within

As always, we believe true skin health starts from within. That’s why we pair our facials with herbal teas, antioxidant-rich diet suggestions, and personalized wellness advice.

Herbs like goji berry, ginseng, and schisandra support your body’s natural detox pathways, while high-antioxidant foods (think berries, greens, and healthy fats) help fight free radicals that contribute to aging and inflammation.

The Gleam Esthetika Approach

Our holistic philosophy means treating the skin as part of the whole body—nourishing it with the right treatments, ingredients, and lifestyle choices. Whether you're looking to heal, glow, or age gracefully, PDRN is a game-changer, and we’re proud to offer it through some of the most advanced Korean facial therapies in the industry.

Ready to experience the benefits for yourself? Book a Korean facial with us and ask about incorporating PDRN. Your skin will thank you.



Tahirah Razak

Licensed Esthetician & Founder of Gleam Esthetika

“Illuminate Your Natural Beauty”

Your Holistic Wellness & Beauty Partner

https://www.gleamesthetika.com
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